SpCO is a breakthrough measurement that noninvasively and continuously measures carboxyhaemoglobin saturation in the blood

Carbon Monoxide

  • > Carbon monoxide (CO) is a colourless and odourless gas that is the byproduct of incomplete combustion of any carbon-containing material.1
  • > Sources of CO include inadequate ventilation of heating sources, automobile exhaust, faulty furnaces, exposure to methylene chloride (an industrial solvent often used for cleaning and as paint thinner), as well as cigarette smoke and smoke from fires.2
  • > Exposure to CO raises levels of circulating carboxyhaemoglobin (COHb) in the blood.

Measuring Carbon Monoxide with SpCO

  • > Pulse CO-oximetry is a continuous and noninvasive method of measuring the levels of carbon monoxide concentration (SpCO) in the blood.
  • > Measurements are taken by placing a sensor on a patient, usually on the fingertip for adults.
  • > Accuracy Range 1-40% with 3% ARMS3.

rainbow SET Technology Platform

Masimo rainbow SET is a noninvasive monitoring platform featuring Masimo SET® Measure-through Motion and Low Perfusion pulse oximetry with the option to measure multiple additional parameters.

  • > Oxygen Saturation (SpO2)
  • > Pulse Rate (PR)
  • > Perfusion Index (PI)
  • > Total Haemoglobin (SpHb®)
  • > Oxygen Content (SpOC™)
  • > Pleth Variability Index (PVI®)
  • > Methaemoglobin (SpMet®)
  • > Carboxyhaemoglobin (SpCO)
  • > Acoustic Respiration Rate (RRa®)


  • > Click here for available SpCO studies.
  • > Click here to receive more information about noninvasive and continuous SpCO.


  • 1 McEvoy, M. Sneak Attack: What makes carbon monoxide so insidious? The Silent Killer. J Emerg Med Svcs. October 2010: 4-9.
  • 2 Weaver, LK. Carbon Monoxide Poisoning. N Engl J Med. 2009; 360(12): 1217-25.
  • 3 The ARMS Accuracy is calculated based upon measurement values that are statistically distributed; approximately 68% of the measured values fell within +/- the ARMS value when compared to the reference device under a controlled study.

SpCO monitoring with Masimo devices is not intended to replace laboratory blood testing. Blood samples should be analyzed by laboratory instruments prior to clinical decision making.

For professional use. See instructions for use for full prescribing information, including indications, contraindications, warnings, and precautions.